Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15443 |
GSK8814
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
GSK8814 is a selective and ATAD2/2B bromodomain chemical probe and inhibitor (binding constant pKd=8.1 and a pKi=8.9 in BROMOscan). GSK8814 displays 500-fold selectivity for ATAD2 over BRD4 BD1. GSK8814 binds to ATAD2 and BRD4 BD1 (pIC50s: 7.3 and 4.6). |